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Cancer Research: The peptide shows significant potential as a tumor suppressor in cancer therapy by targeting and eliminating senescent cancer cells, which often arise from DNA damage and contribute to cancer progression and recurrence

Clinically, GLP-1-based therapies offer the additional advantage of established cardiovascular protection and renal benefits, making them particularly attractive for the large proportion of MASLD patients with comorbid cardiovascular disease or type 2 diabetes

There are no toxicity levels

However, these agents are associated with significant adverse reactions (e.g., electrolyte imbalances, hepatorenal damage, increased infection risk) and exhibit variable individual responses, which complicates the determination of optimal dosage and treatment regimens (Gohda and Murakoshi, 2022

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